Not quite, depending on the build, it's fairly common to see some one-ofs, although I'd recommend starting builds with 3-ofs and 4-ofs, mostly.
However, I ran a Mystical Teachings deck that had AT LEAST 5-6 one-ofs a while ago, and it did pretty well. Testing is the key to figure out quantities. But yeah, start with 3-ofs and 4-ofs.